Main content

Professor Martha Clokie

Professor Martha Clokie tells how she found viruses that destroy antibiotic-resistant bugs

Professor Martha Clokie tells Jim Al-Khalili how she found viruses that destroy antibiotic-resistant bugs by looking in stool samples, her son's nappies and estuary mud.

Could viruses improve our health where antibiotics have failed? As a child, Martha Clokie spent a lot of time collecting seaweed on Scottish beaches. She loves plants and studied botany for many years. But mid-career, she learnt about all the viruses that exist in nature. We tend to focus on the viruses that make us ill but there are trillions of viruses on earth and in the ocean and most of them eat bacteria. When a virus destroys a bacteria that attacks our bodies, then it could be just what the doctor ordered. Our enemy’s enemy is our friend.

Martha became interested in how these viruses - or bacteriophages as they’re known - might be used to treat disease. Before long, Martha had moved from studying African violets in Uganda to looking at stool samples under the microscope and asking fellow parents to donate their babies’ dirty nappies to her research. She spent many years looking for phages that attack the superbug C. difficile, which is responsible for a particularly nasty form of diarrhoea and results in tens of thousands of deaths every year. And she has shown, in animal models at least, that these phages could succeed where antibiotics have failed.

Available now

27 minutes

Last on

Mon 23 Mar 2020 00:32GMT

Broadcasts

  • Mon 16 Mar 2020 20:32GMT
  • Mon 16 Mar 2020 21:32GMT
  • Tue 17 Mar 2020 05:32GMT
  • Tue 17 Mar 2020 06:32GMT
  • Tue 17 Mar 2020 07:32GMT
  • Tue 17 Mar 2020 11:32GMT
  • Tue 17 Mar 2020 15:32GMT
  • Tue 17 Mar 2020 18:32GMT
  • Mon 23 Mar 2020 00:32GMT

Space

The eclipses, spacecraft and astronauts changing our view of the Universe

The Curious Cases of Rutherford and Fry

The Curious Cases of Rutherford and Fry

A pair of scientific sleuths answer your perplexing questions. Ask them anything!

Podcast