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Seven US law enforcement officers have been shot, one of them fatally, in an incident in South Carolina, officials say.

Police in the city of Florence had been responding to a call for help from the sheriff's office.

A gunman had been holding children hostage and was involved in a two-hour stand-off before surrendering and being taken to hospital.

He has not been identified and the motive is unclear.

All the children are now safe, police said.

At a press conference, Florence county Sheriff Kenney Boone said three county sheriff's deputies and four Florence police officers were shot during the incident.

One of the Florence officers, named by local media as Terrence Carraway, 52, died from his injuries.

"Fire was being shot all over," Sheriff Boone said, explaining the suspect's "view of fire" gave him an "advantage" over the officers.

"These officers went there unknowing the firepower this suspect had," he said. "They thought it was a random search warrant."

The condition of the other six is not yet known, although there are fears some may have been seriously wounded.

US President Donald Trump has tweeted about the shooting, quoting South Carolina Governor Henry McMaster.

The - 112 so far this year.

Over 15,000 people have been killed by guns in the United States in 2017, according to .

That figure does not include an estimated 22,000 annual suicides using firearms.